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1

Synthesis and In Vitro Antibacterial Activity of Novel 3-Azabicyclo[3.3.0]octanyl Oxazolidinones

Deepak Bhattarai, Sun H. Lee, Seon H. Seo, Ghilsoo Nam, Soon B. Kang, Ae N. Pae, Eunice E. Kim, Taegwon Oh, Sang-Nae Cho, Gyochang Keum

Journal:

Chemical Biology & Drug Design

Year:

2012

Language:

english

File:

PDF, 146 KB

english, 2012

2

Synthesis and antibacterial activities of new piperidine substituted (5R)-[1,2,3]triazolylmethyl and (5R)-[(4-F-[1,2,3]triazolyl)methyl] oxazolidinones

Shin, Hyo-Nim, Seo, Seon Hee, Choo, Hyunah, Kuem, Gyochang, Choi, Kyung Il, Nam, Ghilsoo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 373 KB

english, 2013

3

ChemInform Abstract: Synthesis and in vitro Antibacterial Activity of 3-[N-Methyl-N-(3-methyl-1,3-thiazolium-2-yl)amino]methyl Cephalosporin Derivatives.

Sung Hoon Kim, Hyenju Son, Ghilsoo Nam, Dae Yoon Chi, Joong Hyup Kim

Journal:

Year:

2000

File:

PDF, 29 KB

2000

4

ChemInform Abstract: Synthesis and Structure—Activity Relationships of Quaternary Ammonium Cephalosporins with 3-Pyrazolylpyridinium Derivatives.

Kwan Young Chang, Sung Hoon Kim, Ghilsoo Nam, Jae Hong Seo, Joong Hyup Kim, Deok-Chan Ha

Journal:

Year:

2000

File:

PDF, 31 KB

2000

5

ChemInform Abstract: Syntheses and Evaluation of Pyrido[2,3-d]pyrimidine-2,4-diones as PDE 4 Inhibitors.

Ghilsoo Nam, Cheol Min Yoon, Euikyung Kim, Chung K. Rhee, Joong Hyup Kim, Jung Hyu Shin, Sung Hoon Kim

Journal:

Year:

2001

File:

PDF, 33 KB

2001

6

ChemInform Abstract: New Cephalosporin Antibiotics with 3-Triazolylpyridiniummethyl Substituents

Kwan Young Chang, Soon Ho Kwon, Ghilsoo Nam, Jae Hong Seo, Sung Hoon Kim, Kyung Il Choi, Joong Hyup Kim, Deok-Chan Ha

Journal:

Year:

2001

File:

PDF, 26 KB

2001

7

Syntheses of β,β-Difluorotryptamines.

Wei-Ping Deng, Ghilsoo Nam, Junfa Fan, Kenneth L. Kirk

Journal:

Year:

2003

File:

PDF, 140 KB

2003

8

Syntheses of Side-Chain Fluorinated Biologically Important Imidazoles and Indoles

Bohumil Dolensky, Ghilsoo Nam, Wei-Ping Deng, Jayan Narayanan, Junfa Fan, Kenneth L. Kirk

Journal:

Year:

2004

File:

PDF, 52 KB

2004

9

ChemInform Abstract: Novel 6-N-Arylcarboxamidopyrazolo[4,3-d]pyrimidin-7-one Derivatives as Potential Anticancer Agents.

Vani N. Devegowda, Jung Hyun Kim, Ki-Cheol Han, Eun Gyeong Yang, Hyunah Choo, Ae Nim Pae, Ghilsoo Nam, Kyung Il Choi

Journal:

Year:

2010

File:

PDF, 24 KB

2010

10

Design, synthesis, and anti-Helicobacter pylori activity of erythromycin A (E)-9-oxime ether derivatives

Ghilsoo Nam, Tae Won Kang, Jung Hyu Shin, Kyung Il Choi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 120 KB

english, 2006

11

Novel 6-N-arylcarboxamidopyrazolo[4,3-d]pyrimidin-7-one derivatives as potential anti-cancer agents

Vani N. Devegowda, Jung Hyun Kim, Ki-Cheol Han, Eun Gyeong Yang, Hyunah Choo, Ae Nim Pae, Ghilsoo Nam, Kyung Il Choi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 273 KB

english, 2010

12

Synthesis and antibacterial activity of new 9-O-arylpropenyloxime ketolides

Ghilsoo Nam, Yang Soo Kim, Kyung Il Choi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 284 KB

english, 2010

13

Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors

Sora Kim, Jin Kyo Jung, Hyo Seon Lee, Youngjae Kim, Jiyoon Kim, Kihang Choi, Du-Jong Baek, Bongjin Moon, Kwang-Seok Oh, Byung Ho Lee, Kye Jung Shin, Ae Nim Pae, Ghilsoo Nam, Eun Joo Roh, Yong Seo Cho,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 526 KB

english, 2011

14

A convenient synthesis of the C-1-phosphonate analogue of UDP-GlcNAc and its evaluation as an inhibitor of O-linked GlcNAc transferase (OGT)

Jan Hajduch, Ghilsoo Nam, Eun Ju Kim, Roland Fröhlich, John A. Hanover, Kenneth L. Kirk

Journal:

Carbohydrate Research

Year:

2008

Language:

english

File:

PDF, 192 KB

english, 2008

15

Syntheses of side-chain fluorinated biologically important imidazoles and indoles

Bohumil Dolensky, Ghilsoo Nam, Wei-Ping Deng, Jayan Narayanan, Junfa Fan, Kenneth L. Kirk

Journal:

Journal of Fluorine Chemistry

Year:

2004

Language:

english

File:

PDF, 159 KB

english, 2004

16

Synthesis and in vitro antibacterial activity of 3-[N-methyl-N-(3-methyl-1,3-thiazolium-2-yl)amino]methyl cephalosporin derivatives

Sung Hoon Kim, Hyenju Son, Ghilsoo Nam, Dae Yoon Chi, Joong Hyup Kim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 126 KB

english, 2000

17

Synthesis and structure–activity relationships of quaternary ammonium cephalosporins with 3-pyrazolylpyridinium derivatives

Kwan Young Chang, Sung Hoon Kim, Ghilsoo Nam, Jae Hong Seo, Joong Hyup Kim, Deok-Chan Ha

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 154 KB

english, 2000

18

Syntheses and evaluation of pyrido[2,3-d]pyrimidine-2,4-diones as PDE 4 inhibitors

Ghilsoo Nam, Cheol Min Yoon, Euikyung Kim, Chung K Rhee, Joong Hyup Kim, Jung Hyu Shin, Sung Hoon Kim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 156 KB

english, 2001

19

Quinazolindione derivatives as potent 5-HT3A receptor antagonists

Byung-Hwan Lee, Min Jung Choi, Mi Na Jo, Hee Jeong Seo, Seung-Yeol Nah, Yong Seo Cho, Ghilsoo Nam, Ae Nim Pae, Hyewhon Rhim, Hyunah Choo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 346 KB

english, 2009

20

20(S)-ginsenoside Rh2, a newly identified active ingredient of ginseng, inhibits NMDA receptors in cultured rat hippocampal neurons

Eunyoung Lee, Sunoh Kim, Kwang Chul Chung, Min-Kyung Choo, Dong-Hyun Kim, Ghilsoo Nam, Hyewhon Rhim

Journal:

European Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 561 KB

english, 2006

21

An Efficient and Selective 1- N -Monoethylation of Sisomicin: Process Development of Netilmicin

Nam, Ghilsoo, Kim, Sung Hoon, Kim, Joong-Hyup, Shin, Jung-Hyu, Jang, Eun-Sook

Journal:

Organic Process Research & Development

Year:

2002

Language:

english

File:

PDF, 71 KB

english, 2002

22

Syntheses of β,β-Difluorotryptamines

Deng, Wei-Ping, Nam, Ghilsoo, Fan, Junfa, Kirk, Kenneth L.

Journal:

Journal of Organic Chemistry

Year:

2003

Language:

english

File:

PDF, 98 KB

english, 2003

23

Synthesis and the 5-HT6 receptor antagonistic effect of 3-arylsulfonylamino-5,6-dihydro-6-substituted pyrazolo[3,4]pyridinones for neuropathic pain treatment

Devegowda, Vani Nelamane, Hong, Jin-Ri, Cho, Sungjin, Lim, Eun Jeong, Choo, Hyunah, Keum, Gyochang, Rhim, Hyewon, Nam, Ghilsoo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 733 KB

english, 2013

24

A novel glucosamine derivative exerts anti-inflammatory actions via inhibition of nuclear factor-kappaB

Shin, Jin-A., Hwang, Ji-Sun, Kim, Song-Yi, Oh, Sei-Kwan, Nam, Ghilsoo, Han, Inn-Oc

Journal:

Neuroscience Letters

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

25

Oxazolopyridines and thiazolopyridines as monoamine oxidase B inhibitors for the treatment of Parkinson’s disease

Park, Hye Ri, Kim, Jiyoon, Kim, Taekeun, Jo, Seonmi, Yeom, Miyoung, Moon, Bongjin, Choo, Il Han, Lee, Jaeick, Lim, Eun Jeong, Park, Ki Duk, Min, Sun-Joon, Nam, Ghilsoo, Keum, Gyochang, Lee, C. Justin,

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.51 MB

english, 2013

26

Aryl Biphenyl-3-ylmethylpiperazines as 5-HT 7 Receptor Antagonists

Kim, Jeeyeon, Kim, Youngjae, Tae, Jinsung, Yeom, Miyoung, Moon, Bongjin, Huang, Xi-Ping, Roth, Bryan L., Lee, Kangho, Rhim, Hyewhon, Choo, Il Han, Chong, Youhoon, Keum, Gyochang, Nam, Ghilsoo, Choo, H

Journal:

Year:

2013

Language:

english

File:

PDF, 1.49 MB

english, 2013

27

Synthesis and Biological Evaluation of Aryloxazole Derivatives as Antimitotic and Vascular-Disrupting Agents for Cancer Therapy

Choi, Min Jeong, No, Eun Sun, Thorat, Dhanaji Achyutrao, Jang, Jae Wan, Yang, Hakkyun, Lee, Jaeick, Choo, Hyunah, Kim, Soo Jin, Lee, Chang Sik, Ko, Soo Young, Lee, Jiyoun, Nam, GhilSoo, Pae, Ae Nim

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 2.92 MB

english, 2013

28

Synthesis and biological evaluation of 1-(isoxazol-5-ylmethylaminoethyl)-4-phenyl tetrahydropyridine and piperidine derivatives as potent T-type calcium channel blockers with antinociceptive effect in a neuropathic pain model

Lee, Ju-Hyeon, Seo, Seon Hee, Lim, Eun Jeong, Cho, Nam-Chul, Nam, Ghilsoo, Kang, Soon Bang, Pae, Ae Nim, Jeong, Nakcheol, Keum, Gyochang

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 853 KB

english, 2014

29

Discovery of aryl-biphenyl-2-ylmethylpiperazines as novel scaffolds for 5-HT7 ligands and role of the aromatic substituents in binding to the target receptor

Kim, Youngjae, Kim, Jeeyeon, Tae, Jinsung, Roth, Bryan L., Rhim, Hyewhon, Keum, Gyochang, Nam, Ghilsoo, Choo, Hyunah

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 837 KB

english, 2013

30

New Efficient Synthesis of Ethyl 2,3-Cycloalkenopyridine-4-carboxylate

Hoon Kim, Sung, Young Kim, Ha, Nam, Ghilsoo, Son, Hyenjoo, Jo Park, Tae, Ja Lee, Sook, Kang, Jahyo, Yoon Chi, Dae, Hyup Kim, Joong

Journal:

Year:

1998

Language:

english

File:

PDF, 345 KB

english, 1998

31

Functional Human 5-HT6 Receptor Assay for High Throughput Screening of Chemical Ligands and Binding Proteins

Kim, Hyun-Ji, Yun, Hyung-Mun, Kim, Taehyun, Nam, Ghilsoo, Roh, Eun, Kostenis, Evi, Choo, Hea-Young, Pae, Ae, Rhim, Hyewhon

Journal:

Combinatorial Chemistry & High Throughput Screening

Year:

2008

Language:

english

File:

PDF, 446 KB

english, 2008

32

Synthesis and Biological Evaluation of 2-Phenylimino-5((5-phenylfuran-2-yl)methylene)thiazolidin-4-ones as IKK2 Inhibitors

Kim, Hee Sook, Shin, Min Jae, Lee, Byungho, Oh, Kwang-Seok, Choo, Hyunah, Pae, Ae Nim, Roh, Eun Joo, Nam, Ghilsoo

Journal:

Bulletin of the Korean Chemical Society

Year:

2015

Language:

english

File:

PDF, 638 KB

english, 2015

33

Discovery of a Nanomolar Multikinase Inhibitor (KST016366): A New Benzothiazole Derivative with Remarkable Broad-Spectrum Antiproliferative Activity

El-Damasy, Ashraf Kareem, Cho, Nam-Chul, Nam, Ghilsoo, Pae, Ae Nim, Keum, Gyochang

Journal:

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

34

Synthesis and T-type calcium channel-blocking effects of aryl(1,5-disubstituted-pyrazol-3-yl)methyl sulfonamides for neuropathic pain treatment

Kim, Jung Hyun, Keum, Gyochang, Chung, Hesson, Nam, Ghilsoo

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 566 KB

english, 2016

35

Synthesis and evaluation of 6-pyrazoylamido-3N-substituted azabicyclo[3,1,0]hexane derivatives as T-type calcium channel inhibitors for treatment of neuropathic pain

Kim, Jung Hyun, Nam, Ghilsoo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.75 MB

english, 2016

36

Synthesis and in Vitro Evaluation of the Antitubercular and Antibacterial Activity of Novel Oxazolidinones Bearing Octahydrocyclopenta[c]pyrrol-2-yl Moieties

Bhattarai, Deepak, Lee, Ju-hyeon, Seo, Seon Hee, Nam, Ghilsoo, Choo, Hyunah, Kang, Soon Bang, Kwak, Jin-Hwan, Oh, Taegwon, Cho, Sang-Nae, Pae, Ae Nim, Kim, Eunice Eunkyeong, Jeong, Nakcheol, Keum, Gyo

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2014

Language:

english

File:

PDF, 1.63 MB

english, 2014

37

New Cephalosporin Antibiotics with 3-Triazolylpyridiniummethyl Substituents.

CHANG, KWAN YOUNG, KWON, SOON HO, NAM, GHILSOO, SEO, JAE HONG, KIM, SUNG HOON, CHOI, KYUNG IL, KIM, JOONG HYUP, HA, DEOK-CHAN

Journal:

The Journal of Antibiotics

Year:

2001

Language:

english

File:

PDF, 179 KB

english, 2001

38

Isoxazoline, Isoxazole, and Oxadiazole Derivatives as M 1 Muscarinic Acetylcholine Receptor Agonists

Muthusamy, Selvaraj, Lee, Soo Min, Huang, Minghua, Cho, Nam-Chul, Nam, Ghilsoo, Pae, Ae Nim, Rhim, Hyewhon, Keum, Gyochang, Choi, Kyung Il

Journal:

Bulletin of the Korean Chemical Society

Year:

2016

Language:

english

File:

PDF, 1.19 MB

english, 2016

39

Evaluation of the Chemical Reporter Analog PNP-6AzGlcNAc as an O-GlcNAcase Substrate

Kim, Eun J., Bond, Michelle R., Nam, Ghilsoo, Hanover, John A.

Journal:

Bulletin of the Korean Chemical Society

Year:

2017

Language:

english

File:

PDF, 547 KB

english, 2017

40

Synthesis and diabetic neuropathic pain-alleviating effects of 2 N -(pyrazol-3-yl)methylbenzo[ d ]isothiazole-1,1-dioxide derivatives

Hong, Jin Ri, Choi, Young Jin, Keum, Gyochang, Nam, Ghilsoo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 902 KB

english, 2017

41

A novel synthetic phosphodiesterase 5 inhibitor, KJH-1002, ameliorates scopolamine-induced cognitive impairments in mice by activating the cGMP/CREB signaling pathway and attenuating oxidative damage

Zhang, Lijun, Seo, Jae Hong, Li, Huan, Nam, Ghilsoo, Yang, Hyun Ok

Journal:

British Journal of Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.11 MB

english, 2018

42

Monitoring of Intracellular Tau Aggregation Regulated by OGA/OGT Inhibitors

Lim, Sungsu, Haque, Md., Nam, Ghilsoo, Ryoo, Nayeon, Rhim, Hyewhon, Kim, Yun

Journal:

International Journal of Molecular Sciences

Year:

2015

Language:

english

File:

PDF, 3.74 MB

english, 2015

43

T-type calcium channel blockers: a patent review (2012–2018)

Journal:

Expert Opinion on Therapeutic Patents

Year:

2018

Language:

english

File:

PDF, 1.34 MB

english, 2018

44

OâGlcNAcase: emerging mechanism, substrate recognition and small molecule inhibitors

Elbatrawy, Ahmed A., Kim, Eun Ju, Nam, Ghilsoo

Journal:

Year:

2020

File:

PDF, 1.94 MB

2020

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